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Abner M Mhashilkar Selected Research

interleukin-24 (ST16)

2/2006MDA-7/IL-24-based cancer gene therapy: translation from the laboratory to the clinic.
5/2005mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
2/2005Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
12/2004Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
3/2004The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells.
8/2003MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells.

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Abner M Mhashilkar Research Topics

Disease

15Neoplasms (Cancer)
02/2006 - 01/2003
14Melanoma (Melanoma, Malignant)
02/2006 - 04/2002
4Lung Neoplasms (Lung Cancer)
02/2005 - 04/2002
2Colorectal Neoplasms (Colorectal Cancer)
05/2005 - 11/2003
2Prostatic Neoplasms (Prostate Cancer)
05/2005 - 03/2005
1Wounds and Injuries (Trauma)
11/2012
1Pancreatic Neoplasms (Pancreatic Cancer)
05/2005
1Ovarian Neoplasms (Ovarian Cancer)
04/2005
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
02/2005
1Nevus (Nevi)
05/2004
1Disease Progression
05/2004
1Neoplasm Metastasis (Metastasis)
04/2004
1Ataxia Telangiectasia (Louis Bar Syndrome)
11/2003
1Malignant Mesothelioma
12/2002

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
05/2005 - 06/2002
6interleukin-24 (ST16)IBA
02/2006 - 08/2003
6CytokinesIBA
02/2006 - 08/2003
5InterleukinsIBA
04/2005 - 08/2003
3CaspasesIBA
03/2005 - 03/2004
2beta CateninIBA
05/2005 - 08/2003
2interleukin-20 receptorIBA
05/2005 - 12/2004
2DNA (Deoxyribonucleic Acid)IBA
05/2005 - 11/2003
2eIF-2 Kinase (eIF 2 Kinase)IBA
02/2005 - 04/2002
2Interleukin-10 (Interleukin 10)IBA
12/2004 - 05/2004
2LigandsIBA
12/2004 - 08/2003
2Cadherins (E-Cadherin)IBA
08/2003 - 08/2002
1Biocompatible Materials (Biomaterials)IBA
11/2012
1interleukin 20 (IL-20)IBA
05/2005
1Glycogen Synthase Kinase 3IBA
05/2005
1Actins (F Actin)IBA
05/2005
1Ribosomal Proteins (Ribosomal Protein)IBA
05/2005
1Small Interfering RNA (siRNA)IBA
04/2005
1Transcription Factors (Transcription Factor)IBA
04/2005
1Fas Ligand Protein (Fas Ligand)IBA
04/2005
1Activating Transcription Factor 2IBA
04/2005
1fas Receptor (CD95 Antigen)IBA
04/2005
1Sulindac (Copal)FDA LinkGeneric
02/2005
1Caspase 3 (Caspase-3)IBA
02/2005
1Caspase 9IBA
02/2005
1Pharmaceutical PreparationsIBA
02/2005
1Interleukin-1 (Interleukin 1)IBA
10/2004
1NF-kappa B (NF-kB)IBA
10/2004
1Interleukin-6 (Interleukin 6)IBA
10/2004
1Complementary DNA (cDNA)IBA
05/2004
11,2- dioleoyloxy- 3- (trimethylammonium)propaneIBA
04/2004
1Phosphates (Orthophosphate)IBA
04/2004
1XanthineIBA
11/2003
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
11/2003
1TensinsIBA
11/2003
1Caffeine (No Doz)FDA LinkGeneric
11/2003
1Phosphotransferases (Kinase)IBA
11/2003
1Therapeutic UsesIBA
11/2003
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
11/2003
1Antineoplastic Agents (Antineoplastics)IBA
11/2003
1Interleukin-4 (Interleukin 4)IBA
10/2003
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2003
1InterferonsIBA
10/2003
1Interleukin-12 (IL 12)IBA
10/2003
1ChemokinesIBA
10/2003
1Colony-Stimulating Factors (Colony Stimulating Factor)IBA
10/2003
1Biological ProductsIBA
10/2003
1Hemoglobins (Hemoglobin)IBA
08/2003
1interleukin-22 receptor (IL-22R)IBA
08/2003
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2003
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
08/2002
1Prokaryotic Initiation Factor-2IBA
04/2002
1Double-Stranded RNA (RNA, Double Stranded)IBA
04/2002

Therapy/Procedure

5Therapeutics
11/2012 - 12/2002
2Drug Therapy (Chemotherapy)
02/2006 - 05/2005
1Radiotherapy
02/2006
1Aftercare (After-Treatment)
01/2003